LRRC4C Antikörper (AA 561-640) (Cy3)

Produktnummer ABIN720299

Der Kaninchen Polyklonal Anti-LRRC4C-Antikörper wurde für WB, IF (cc) und IF (p) validiert. Er ist geeignet, LRRC4C in Proben von Human, Maus und Ratte zu detektieren.

Kurzübersicht für LRRC4C Antikörper (AA 561-640) (Cy3) (ABIN720299)

Target: LRRC4C (Leucine Rich Repeat Containing 4C (LRRC4C))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser LRRC4C Antikörper ist konjugiert mit Cy3

Applikation: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Produktdetails anti-LRRC4C Antikörper (Cy3)

Bindungsspezifität: AA 561-640

Kreuzreaktivität: Human, Maus, Ratte

Homologie: Dog,Cow,Horse,Rabbit

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human Netrin G1 ligand

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu LRRC4C

Target: LRRC4C (Leucine Rich Repeat Containing 4C (LRRC4C))

Andere Bezeichnung: Netrin G1 ligand

Hintergrund:

Synonyms: Leucine rich repeat containing 4C, Leucine-rich repeat-containing protein 4C, LRC4C_HUMAN, Lrrc4C, Netrin-G1 ligand, NGL 1, NGL-1, NGL1.

Background: NGL-1 is a single pass type I membrane protein that acts as a cell adhesion molecule. It contains nine leucine-rich repeats (LRR) and one Ig-like C2-type domain. NGL-1 is predominantly expressed in the striatum and the cerebral cortex of both the embryonic and adult brain. NGL-1 specifically interacts with Netrin G1 (a molecule involved in axon guidance in the developing central nervous system) via its LRR region. NGL-1 plays a role in the regulation of neurite outgrowth of developing thalamic neurons. Soluble NGL-1 inhibits thalamic axon outgrowth while NGL-1 that is bound to the surface of developing thalamocortical axons stimulates growth. NGL-1 also interacts with Whirlin possibly stablizing interstereociliar links.

Gen-ID: 22854

Pathways: Synaptic Membrane