Rekombinanter ACE2 Antikörper (AA 705-805)

Produktnummer ABIN7477373

Der Kaninchen Monoklonal Anti-ACE2-Antikörper wurde für IHC validiert. Er ist geeignet, ACE2 in Proben von Human zu detektieren.

Kurzübersicht für Rekombinanter ACE2 Antikörper (AA 705-805) (ABIN7477373)

Target: ACE2 (Angiotensin I Converting Enzyme 2 (ACE2))

Antikörpertyp: Recombinant Antibody

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Monoklonal

Konjugat: Dieser ACE2 Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (IHC)

Klon: MSVA-919R

Produktdetails anti-ACE2 Antikörper

Bindungsspezifität: AA 705-805

Immunogen: Recombinant fragment (around aa705-805) of human ACE2 (exact sequence is proprietary)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IHC 1:100-1:200

Kommentare:

Positive Control: Kidney: Cells of proximal tubuli should show a moderate to strong ACE2 immunostaining with accentuation of the staining at the apical membrane.

Negative Control: Kidney: Cells of distal tubuli and glomeruli should not show ACE2 immunostaining.

Protokoll: Manual Protocol: Freshly cut sections should be used (less than 10 days between cutting and staining). Heat-induced antigen retrieval for 5 minutes in an autoclave at 121 °C in pH 7,8 Target Retrieval Solution buffer. Apply the antibody at a dilution of 1:150 at 37 °C for 60 minutes. Visualization of bound antibody by the EnVision Kit (Dako, Agilent) according to the manufacturer's directions.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Lagerung: 4 °C,-20 °C,-80 °C

Informationen zur Lagerung: Antibody with azide - store at 2 to 8 °C. Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non- hazardous.

Details zu ACE2

Target: ACE2 (Angiotensin I Converting Enzyme 2 (ACE2))

Andere Bezeichnung: ACE2

Hintergrund: Angiotensin I converting enzyme 2,ACE2 antibody validated for immunohistochemistry on 76 different Normal Tissues

UniProt: Q9BYF1

Pathways: ACE Inhibitor Pathway, Peptide Hormone Metabolism, Regulation of Systemic Arterial Blood Pressure by Hormones, Feeding Behaviour