SETD2 Antikörper (N-Term)

Produktnummer ABIN7469603

Dieses Anti-SETD2-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von SETD2 in WB, IF, IHC (p) und ICC. Geeignet für Human.

Kurzübersicht für SETD2 Antikörper (N-Term) (ABIN7469603)

Target: SETD2 (SET Domain Containing 2 (SETD2))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SETD2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC)

Güteklasse: KO Validated

Produktdetails anti-SETD2 Antikörper

Bindungsspezifität: N-Term

Kreuzreaktivität: Human

Aufreinigung: Purified by antigen-affinity chromatography.

Immunogen: Recombinant protein encompassing a sequence within the N-terminus region of human HYPB/SETD2. The exact sequence is proprietary.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB: 1:500-1:3000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Kommentare:

Validation: KO/KD

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.96 mg/mL

Buffer: 1XPBS ( pH 7), 20 % Glycerol, 0.025 % ProClin 300

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Details zu SETD2

Target: SETD2 (SET Domain Containing 2 (SETD2))

Andere Bezeichnung: HYPB/SETD2

Hintergrund:

Synonyms: SET domain containing 2, histone lysine methyltransferase , HBP231 , HIF-1 , HIP-1 , HSPC069 , HYPB , KMT3A , LLS , SET2 , p231HBP

Background: Huntington's disease (HD), a neurodegenerative disorder characterized by loss of striatal neurons, is caused by an expansion of a polyglutamine tract in the HD protein huntingtin. This gene encodes a protein belonging to a class of huntingtin interacting proteins characterized by WW motifs. This protein is a histone methyltransferase that is specific for lysine-36 of histone H3, and methylation of this residue is associated with active chromatin. This protein also contains a novel transcriptional activation domain and has been found associated with hyperphosphorylated RNA polymerase II. [provided by RefSeq]

Molekulargewicht: 288 kDa

Gen-ID: 29072

UniProt: Q9BYW2

Pathways: Tube Formation