RHEB Antikörper

Produktnummer ABIN7469570

Dieses Anti-RHEB-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von RHEB in WB. Geeignet für Human.

Kurzübersicht für RHEB Antikörper (ABIN7469570)

Target: RHEB (Ras Homolog Enriched in Brain (RHEB))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser RHEB Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-RHEB Antikörper

Kreuzreaktivität: Human

Aufreinigung: Purified by antigen-affinity chromatography.

Immunogen: Recombinant protein encompassing a sequence within the center region of human Rheb. The exact sequence is proprietary.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB: 1:500-1:3000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Kommentare:

Positive Control: A431

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: 0.1M Tris-Glycine ( pH 7), 10 % Glycerol, 0.01 % Thimerosal

Konservierungsmittel: Thimerosal (Merthiolate)

Vorsichtsmaßnahmen: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Details zu RHEB

Target: RHEB (Ras Homolog Enriched in Brain (RHEB))

Andere Bezeichnung: Rheb

Hintergrund:

Synonyms: Ras homolog, mTORC1 binding , RHEB2

Background: This gene is a member of the small GTPase superfamily and encodes a lipid-anchored, cell membrane protein with five repeats of the RAS-related GTP-binding region. This protein is vital in regulation of growth and cell cycle progression due to its role in the insulin/TOR/S6K signaling pathway. The protein has GTPase activity and shuttles between a GDP-bound form and a GTP-bound form, and farnesylation of the protein is required for this activity. Three pseudogenes have been mapped, two on chromosome 10 and one on chromosome 22. [provided by RefSeq]

Molekulargewicht: 20 kDa

Gen-ID: 6009

UniProt: Q15382

Pathways: RTK Signalweg