TSG101 Antikörper (AA 167-374)

Produktnummer ABIN7469107

Der Maus Monoklonal Anti-TSG101-Antikörper wurde für WB, IHC, ELISA, IP, IF, IHC (p), FACS, ICC, IEM und IHC (ff) validiert. Er ist geeignet, TSG101 in Proben von Human zu detektieren.

Kurzübersicht für TSG101 Antikörper (AA 167-374) (ABIN7469107)

Target: TSG101 (Tumor Susceptibility Gene 101 (TSG101))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser TSG101 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunoprecipitation (IP), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS), Immunocytochemistry (ICC), Immunoelectron Microscopy (IEM), Immunohistochemistry (Free Floating) (IHC (ff))

Güteklasse: KO Validated

Klon: 4A10

Produktdetails anti-TSG101 Antikörper

Bindungsspezifität: AA 167-374

Spezifität: Knockdown/Knockout validation was supported by references (PMID:27226592)

Kreuzreaktivität: Hund, Hamster, Human, Affe, Maus, Schwein, Ratte, Zebrafisch (Danio rerio)

Aufreinigung: Purified by antigen-affinity chromatography.

Immunogen: Amino acids 167-374 of TSG101 protein expressed in E. coli.

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: WB: 1:500-1:3000. ICC/IF: 1:500-1:1000. IHC-P: 1:100-1:1000. FACS: 1:25-1:200. EM: 1:10. IHC: 1:100. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Kommentare:

Positive Control: 293T , K562 , THP-1 , HL-60 , Neuro 2A , C8D30 , NIH-3T3 , Raw264.7 , C2C12 , NIH-3T3 , JC , BCL-1 Validation: KO/KD, Orthogonal, Overexpression, Recombinant antibody

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1.8 mg/mL

Buffer: PBS, No Preservative

Konservierungsmittel: Without preservative

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Details zu TSG101

Target: TSG101 (Tumor Susceptibility Gene 101 (TSG101))

Andere Bezeichnung: tumor susceptibility 101

Hintergrund:

Synonyms: tumor susceptibility 101 , TSG10 , VPS23

Background: The protein encoded by this gene belongs to a group of apparently inactive homologs of ubiquitin-conjugating enzymes. The gene product contains a coiled-coil domain that interacts with stathmin, a cytosolic phosphoprotein implicated in tumorigenesis. The protein may play a role in cell growth and differentiation and act as a negative growth regulator. In vitro steady-state expression of this tumor susceptibility gene appears to be important for maintenance of genomic stability and cell cycle regulation. Mutations and alternative splicing in this gene occur in high frequency in breast cancer and suggest that defects occur during breast cancer tumorigenesis and/or progression. [provided by RefSeq, Jul 2008]

Molekulargewicht: 44 kDa

Gen-ID: 7251

UniProt: Q99816