TRPS1 Antikörper

Produktnummer ABIN7469087

Produktdetails anti-TRPS1 Antikörper

Target: TRPS1 (Trichorhinophalangeal Syndrome I (TRPS1))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TRPS1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Kreuzreaktivität: Human

Aufreinigung: Purified by antigen-affinity chromatography.

Immunogen: Recombinant protein encompassing a sequence within the center region of human TRPS1. The exact sequence is proprietary.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB: 1:500-1:3000. IHC-P: 1:100-1:2500. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Kommentare:

Positive Control: MCF-7 , MCF-7 nuclear extract Validation: Orthogonal

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: 1XPBS ( pH 7), 20 % Glycerol, 0.025 % ProClin 300

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Details zu TRPS1

Target: TRPS1 (Trichorhinophalangeal Syndrome I (TRPS1))

Andere Bezeichnung: transcriptional repressor GATA binding 1 (TRPS1 Produkte)

Synonyme: GC79 antikoerper, LGCR antikoerper, AI115454 antikoerper, AI447310 antikoerper, D15Ertd586e antikoerper, transcriptional repressor GATA binding 1 antikoerper, transcriptional repressor GATA binding 1 S homeolog antikoerper, Trps1 antikoerper, TRPS1 antikoerper, trps1.S antikoerper

Hintergrund:

Synonyms: transcriptional repressor GATA binding 1 , GC79 , LGCR

Background: This gene encodes a transcription factor that represses GATA-regulated genes and binds to a dynein light chain protein. Binding of the encoded protein to the dynein light chain protein affects binding to GATA consensus sequences and suppresses its transcriptional activity. Defects in this gene are a cause of tricho-rhino-phalangeal syndrome (TRPS) types I-III. [provided by RefSeq]

Molekulargewicht: 142 kDa

Gen-ID: 7227

UniProt: Q9UHF7

Pathways: Protein targeting to Nucleus