TRPS1 Antikörper (AA 1000-1050)

Produktnummer ABIN7454931

Produktdetails anti-TRPS1 Antikörper

Target: TRPS1 (Trichorhinophalangeal Syndrome I (TRPS1))

Bindungsspezifität: AA 1000-1050

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TRPS1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))

Verwendungszweck: Rabbit anti-TRPS1 Antibody, Affinity Purified

Homologie: Mouse

Aufreinigung: Affinity Purified

Immunogen: between AA 1000 and 1050

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise:

IHC: 1:500 - 1:2,000. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.

IP: 2 - 10 μg/mg lysate

WB: 1:2,000 - 1:10,000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Haltbarkeit: 12 months

Details zu TRPS1

Target: TRPS1 (Trichorhinophalangeal Syndrome I (TRPS1))

Andere Bezeichnung: TRPS1 (TRPS1 Produkte)

Synonyme: GC79 antikoerper, LGCR antikoerper, AI115454 antikoerper, AI447310 antikoerper, D15Ertd586e antikoerper, transcriptional repressor GATA binding 1 antikoerper, transcriptional repressor GATA binding 1 S homeolog antikoerper, Trps1 antikoerper, TRPS1 antikoerper, trps1.S antikoerper

Hintergrund: Background: Tricho-rhino-phalangeal syndrome type I protein (TRPS1) is a transcription factor that represses GATA-regulated genes and binds to a dynein light chain protein. Binding of TRPS1 to the dynein light chain protein affects binding to GATA consensus sequences and suppresses its transcriptional activity. Defects in the TRPS1 gene are a cause of tricho-rhino-phalangeal syndrome (TRPS) types I-III [taken from NCBI Entrez Gene (Gene ID: 7227)].

Gen-ID: 7227

UniProt: Q9UHF7

Pathways: Protein targeting to Nucleus