SBDS Antikörper

Produktnummer ABIN7468968

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch SBDS in WB, IF, ICC, IP und IHC (p). Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für SBDS Antikörper (ABIN7468968)

Target: SBDS (Shwachman-Bodian-Diamond Syndrome (SBDS))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SBDS Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF), Immunocytochemistry (ICC), Immunoprecipitation (IP), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Güteklasse: KO Validated

Produktdetails anti-SBDS Antikörper

Spezifität: Knockdown/Knockout validation was supported by references (PMID:26990993)

Kreuzreaktivität: Human, Maus

Aufreinigung: Purified by antigen-affinity chromatography.

Immunogen: Full length human SBDS Recombinant protein.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Kommentare:

Positive Control: H1299 , HeLa , HepG2 , Mouse liver Validation: KO/KD

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.69 mg/mL

Buffer: 0.1M Tris-Glycine ( pH 7), 10 % Glycerol, 0.01 % Thimerosal

Konservierungsmittel: Thimerosal (Merthiolate)

Vorsichtsmaßnahmen: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Details zu SBDS

Target: SBDS (Shwachman-Bodian-Diamond Syndrome (SBDS))

Andere Bezeichnung: SBDS ribosome maturation factor

Hintergrund:

Synonyms: SBDS ribosome maturation factor , CGI-97 , SDS , SWDS

Background: This gene encodes a member of a highly conserved protein family that exists from archaea to vertebrates and plants. The encoded protein may function in RNA metabolism. Mutations within this gene are associated with Shwachman-Bodian-Diamond syndrome. An alternative transcript has been described, but its biological nature has not been determined. This gene has a closely linked pseudogene that is distally located. [provided by RefSeq]

Molekulargewicht: 29 kDa

Gen-ID: 51119

UniProt: Q9Y3A5

Pathways: Ribonucleoprotein Complex Subunit Organization, Ribosome Assembly