Splicing factor U2AF 26 kDa subunit (U2AF1L4) Antikörper

Produktnummer ABIN7467804

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch in IF und ICC. Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für Splicing factor U2AF 26 kDa subunit (U2AF1L4) Antikörper (ABIN7467804)

Target: Splicing factor U2AF 26 kDa subunit (U2AF1L4)

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Unkonjugiert

Applikation: Immunofluorescence (IF), Immunocytochemistry (ICC)

Produktdetails

Kreuzreaktivität: Human

Aufreinigung: Purified by antigen-affinity chromatography.

Immunogen: Recombinant protein encompassing a sequence within the center region of human U2AF1L4. The exact sequence is proprietary.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: ICC/IF: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: 1XPBS ( pH 7), 20 % Glycerol, 0.01 % Thimerosal

Konservierungsmittel: Thimerosal (Merthiolate)

Vorsichtsmaßnahmen: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Antigendetails

Target: Splicing factor U2AF 26 kDa subunit (U2AF1L4)

Andere Bezeichnung: U2 small nuclear RNA auxiliary factor 1 like 4

Hintergrund: U2 small nuclear RNA auxiliary factor 1 like 4 , U2AF1-RS3 , U2AF1L3 , U2AF1L3V1 , U2AF1RS3 , U2af26,RNA-binding protein that function as a pre-mRNA splicing factor. Plays a critical role in both constitutive and enhancer-dependent splicing by mediating protein-protein interactions and protein-RNA interactions required for accurate 3'-splice site selection. Acts by enhancing the binding of U2AF2 to weak pyrimidine tracts. Also participates in the regulation of alternative pre-mRNA splicing. Activates exon 5 skipping of PTPRC during T cell activation, an event reversed by GFI1. Binds to RNA at the AG dinucleotide at the 3'-splice site.

Molekulargewicht: 22 kDa

Gen-ID: 199746

UniProt: Q8WU68