Splicing factor U2AF 26 kDa subunit (U2AF1L4) (N-Term) Antikörper

Produktnummer ABIN2778747

Der Kaninchen Polyklonal anti-Splicing factor U2AF 26 kDa subunit Antikörper wird verwendet zum Nachweis von Splicing factor U2AF 26 kDa subunit in Proben von Human, Rind (Kuh), Hund, Meerschweinchen, Pferd, Maus, Kaninchen, Ratte, Zebrafisch (Danio rerio) und Ziege. Er wurde validiert für WB.

Kurzübersicht für Splicing factor U2AF 26 kDa subunit (U2AF1L4) (N-Term) Antikörper (ABIN2778747)

Target: Splicing factor U2AF 26 kDa subunit (U2AF1L4)

Reaktivität: Human, Rind (Kuh), Hund, Meerschweinchen, Pferd, Maus, Kaninchen, Ratte, Zebrafisch (Danio rerio), Ziege

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails

Bindungsspezifität: N-Term

Verwendungszweck: U2AF1L4 Antibody - N-terminal region

Sequenz: KIGVCRHGDR CSRLHNKPTF SQTIVLLNLY RNPQNTAQTA DGSHCHVSDV

Homologie: Cow: 100%, Dog: 100%, Goat: 79%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against U2AF1L4. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N-terminal region of Human U2AF1L4

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP40325-100UG

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: prevent freeze-thaw cycles

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Antigendetails

Target: Splicing factor U2AF 26 kDa subunit (U2AF1L4)

Andere Bezeichnung: U2AF1L4

Hintergrund:

Background Information: U2AF1L4 is a RNA-binding protein that function as a pre-mRNA splicing factor. It plays a critical role in both constitutive and enhancer-dependent splicing by mediating protein-protein interactions and protein-RNA interactions required for accurate 3'-splice site selection. It acts by enhancing the binding of U2AF2 to weak pyrimidine tracts and also participates in the regulation of alternative pre-mRNA splicing. It activates exon 5 skipping of PTPRC during T-cell activation, an event reversed by GFI1. U2AF1L4 binds to RNA at the AG dinucleotide at the 3'-splice site.

Gene Name: U2 small nuclear RNA auxiliary factor 1

Alternative Symbols: U2af26, U2AF1L3, U2AF1RS3, U2AF1-RS3, U2AF1L3V1

Protein Name: Splicing factor U2AF 26 kDa subunit

Molekulargewicht: 24kDa

Gen-ID: 199746

UniProt: Q8WU68