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LIM Domain Binding 3 Protein Antikörper

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch LIM Domain Binding 3 Protein in WB und IHC (p). Er zeigt eine Reaktivität gegenüber Human.
Produktnummer ABIN7467111

Kurzübersicht für LIM Domain Binding 3 Protein Antikörper (ABIN7467111)

Target

Alle LIM Domain Binding 3 Protein (LDB3) Antikörper anzeigen
LIM Domain Binding 3 Protein (LDB3) (LIM Domain Binding 3 (LDB3))

Reaktivität

  • 21
  • 8
  • 3
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Human

Wirt

  • 18
  • 4
  • 1
Kaninchen

Klonalität

  • 20
  • 3
Polyklonal

Konjugat

  • 18
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser LIM Domain Binding 3 Protein Antikörper ist unkonjugiert

Applikation

  • 22
  • 14
  • 5
  • 4
  • 1
Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • Kreuzreaktivität

    Human, Maus, Ratte

    Aufreinigung

    Purified by antigen-affinity chromatography.

    Immunogen

    Recombinant protein encompassing a sequence within the center region of human LDB3. The exact sequence is proprietary.

    Isotyp

    IgG
  • Applikationshinweise

    WB: 1:500-1:3000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

    Kommentare

    Positive Control: NT2D1 , RD , rat muscle , mouse muscle

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Konzentration

    1 mg/mL

    Buffer

    1XPBS ( pH 7), 1 % BSA, 20 % Glycerol, 0.01 % Thimerosal

    Konservierungsmittel

    Thimerosal (Merthiolate)

    Vorsichtsmaßnahmen

    This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Lagerung

    4 °C,-20 °C

    Informationen zur Lagerung

    Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • Target

    LIM Domain Binding 3 Protein (LDB3) (LIM Domain Binding 3 (LDB3))

    Andere Bezeichnung

    LIM domain binding 3

    Hintergrund

    LIM domain binding 3 , CMD1C , CMH24 , CMPD3 , CYPHER , LDB3Z1 , LDB3Z4 , LVNC3 , MFM4 , ORACLE , PDLIM6 , ZASP,This gene encodes a PDZ domain-containing protein. PDZ motifs are modular protein-protein interaction domains consisting of 80-120 amino acid residues. PDZ domain-containing proteins interact with each other in cytoskeletal assembly or with other proteins involved in targeting and clustering of membrane proteins. The protein encoded by this gene interacts with alpha-actinin-2 through its N-terminal PDZ domain and with protein kinase C via its C-terminal LIM domains. The LIM domain is a cysteine-rich motif defined by 50-60 amino acids containing two zinc-binding modules. This protein also interacts with all three members of the myozenin family. Mutations in this gene have been associated with myofibrillar myopathy and dilated cardiomyopathy. Alternatively spliced transcript variants encoding different isoforms have been identified, all isoforms have N-terminal PDZ domains while only longer isoforms (1 and 2) have C-terminal LIM domains. [provided by RefSeq]

    Molekulargewicht

    77 kDa

    Gen-ID

    11155

    UniProt

    O75112
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