LIM Domain Binding 3 Protein Antikörper (AA 235-262)

Produktnummer ABIN1538145

Der Kaninchen Polyklonal anti-LIM Domain Binding 3 Protein Antikörper (Klon RB36787) (ABIN1538145) detektiert spezifisch LIM Domain Binding 3 Protein in WB. Dieser Antikörper reagiert spezifisch mit Proben aus Human.

Kurzübersicht für LIM Domain Binding 3 Protein Antikörper (AA 235-262) (ABIN1538145)

Target: LIM Domain Binding 3 Protein (LDB3) (LIM Domain Binding 3 (LDB3))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser LIM Domain Binding 3 Protein Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Klon: RB36787

Produktdetails anti-LIM Domain Binding 3 Protein Antikörper

Bindungsspezifität: AA 235-262

Aufreinigung: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This LDB3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 235-262 amino acids from the Central region of human LDB3.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: WB: 1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: LDB3 Antibody (Center) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, keep at -20 °C.

Haltbarkeit: 6 months

Details zu LIM Domain Binding 3 Protein

Target: LIM Domain Binding 3 Protein (LDB3) (LIM Domain Binding 3 (LDB3))

Andere Bezeichnung: LDB3

Hintergrund: This gene encodes a PDZ domain-containing protein. PDZ motifs are modular protein-protein interaction domains consisting of 80-120 amino acid residues. PDZ domain-containing proteins interact with each other in cytoskeletal assembly or with other proteins involved in targeting and clustering of membrane proteins. The protein encoded by this gene interacts with alpha-actinin-2 through its N-terminal PDZ domain and with protein kinase C via its C-terminal LIM domains. The LIM domain is a cysteine-rich motif defined by 50-60 amino acids containing two zinc-binding modules. This protein also interacts with all three members of the myozenin family. Mutations in this gene have been associated with myofibrillar myopathy and dilated cardiomyopathy. Alternatively spliced transcript variants encoding different isoforms have been identified, all isoforms have N-terminal PDZ domains while only longer isoforms (1, 2 and 5) have C-terminal LIM domains. [provided by RefSeq].

Molekulargewicht: 77135

Gen-ID: 11155

NCBI Accession: NP_001073583, NP_001073584, NP_001073585, NP_001165081, NP_001165082, NP_009009

UniProt: O75112