MADD Antikörper
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- Target Alle MADD Antikörper anzeigen
- MADD (MAP-Kinase Activating Death Domain (MADD))
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Reaktivität
- Maus
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser MADD Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB)
- Kreuzreaktivität
- Maus
- Aufreinigung
- Purified by antigen-affinity chromatography.
- Immunogen
- Carrier-protein conjugated synthetic peptide encompassing a sequence within the center region of mouse MADD. The exact sequence is proprietary.
- Isotyp
- IgG
- Top Product
- Discover our top product MADD Primärantikörper
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- Applikationshinweise
- WB: 1:500-1:3000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
- Kommentare
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Positive Control: Neuro2A , Raw264.7
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1.39 mg/mL
- Buffer
- 1XPBS ( pH 7), 20 % Glycerol, 0.025 % ProClin 300
- Konservierungsmittel
- ProClin
- Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- 4 °C,-20 °C
- Informationen zur Lagerung
- Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
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- Target
- MADD (MAP-Kinase Activating Death Domain (MADD))
- Andere Bezeichnung
- MAP-kinase activating death domain (MADD Produkte)
- Hintergrund
- MAP-kinase activating death domain , 9630059K23Rik , IG20,Plays a significant role in regulating cell proliferation, survival and death through alternative mRNA splicing. Converts GDP-bound inactive form of RAB3A, RAB3C and RAB3D to the GTP-bound active forms. Component of the TNFRSF1A signaling complex: MADD links TNFRSF1A with MAP kinase activation. Plays an important regulatory role in physiological cell death (TNF-alpha-induced, caspase-mediated apoptosis).
- Molekulargewicht
- 175 kDa
- Gen-ID
- 228355
- UniProt
- Q80U28
- Pathways
- Caspase Kaskade in der Apoptose
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