Progesterone Receptor Antikörper (AA 1-101)

Produktnummer ABIN7466678

Dieses Anti-Progesterone Receptor-Antikörper ist ein Maus Monoklonal-Antikörper zur Detektion von Progesterone Receptor in WB. Geeignet für Human.

Kurzübersicht für Progesterone Receptor Antikörper (AA 1-101) (ABIN7466678)

Target: Progesterone Receptor (PGR)

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser Progesterone Receptor Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Klon: 4D8

Produktdetails anti-Progesterone Receptor Antikörper

Bindungsspezifität: AA 1-101

Spezifität: This antibody recognizes both Form A (94 kDa) and Form B (120 kDa) of the human progesterone receptor (PgR)

Kreuzreaktivität: Human

Aufreinigung: Protein G purified

Immunogen: 6-His fusion protein containing the region encoding amino acids 1-101 of the human progesterone receptor expressed in E. coli.

Isotyp: IgG2a

Anwendungsinformationen

Applikationshinweise: WB: 1 - 5 μg/mL. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Kommentare:

Positive Control: MCF7 lysate (GTX23871) & recombinant protein

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS pH 7.2, No Preservative

Konservierungsmittel: Without preservative

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Details zu Progesterone Receptor

Target: Progesterone Receptor (PGR)

Andere Bezeichnung: progesterone receptor

Hintergrund: Progesterone receptor , NR3C3 , PR,This gene encodes a member of the steroid receptor superfamily. The encoded protein mediates the physiological effects of progesterone, which plays a central role in reproductive events associated with the establishment and maintenance of pregnancy. This gene uses two distinct promotors and translation start sites in the first exon to produce several transcript variants, both protein coding and non-protein coding. Two of the isoforms (A and B) are identical except for an additional 165 amino acids found in the N-terminus of isoform B and mediate their own response genes and physiologic effects with little overlap. [provided by RefSeq, Sep 2015]

Molekulargewicht: 99 kDa

Gen-ID: 5241

UniProt: P06401

Pathways: Nuclear Receptor Transcription Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Steroid Hormone Mediated Signaling Pathway, Smooth Muscle Cell Migration