BMPR1A Antikörper

Produktnummer ABIN7466196

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch BMPR1A in WB. Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für BMPR1A Antikörper (ABIN7466196)

Target: BMPR1A (Bone Morphogenetic Protein Receptor 1A (BMPR1A))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser BMPR1A Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-BMPR1A Antikörper

Kreuzreaktivität: Human

Aufreinigung: Purified by antigen-affinity chromatography.

Immunogen: Recombinant protein encompassing a sequence within the center region of human BMPR1A. The exact sequence is proprietary.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB: 1:500-1:3000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Kommentare:

Positive Control: human BMPR1A-transfected 293T cells

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: 1XPBS ( pH 7), 20 % Glycerol, 0.01 % Thimerosal

Konservierungsmittel: Thimerosal (Merthiolate)

Vorsichtsmaßnahmen: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Details zu BMPR1A

Target: BMPR1A (Bone Morphogenetic Protein Receptor 1A (BMPR1A))

Andere Bezeichnung: bone morphogenetic protein receptor type 1A

Hintergrund: Bone morphogenetic protein receptor type 1A , 10q23del , ACVRLK3 , ALK3 , CD292 , SKR5,The bone morphogenetic protein (BMP) receptors are a family of transmembrane serine/threonine kinases that include the type I receptors BMPR1A and BMPR1B and the type II receptor BMPR2. These receptors are also closely related to the activin receptors, ACVR1 and ACVR2. The ligands of these receptors are members of the TGF-beta superfamily. TGF-betas and activins transduce their signals through the formation of heteromeric complexes with 2 different types of serine (threonine) kinase receptors: type I receptors of about 50-55 kD and type II receptors of about 70-80 kD. Type II receptors bind ligands in the absence of type I receptors, but they require their respective type I receptors for signaling, whereas type I receptors require their respective type II receptors for ligand binding. [provided by RefSeq]

Molekulargewicht: 60 kDa

Gen-ID: 657

UniProt: P36894

Pathways: Stem Cell Maintenance