C4A Antikörper (N-Term)

Produktnummer ABIN7466047

Der Kaninchen Polyklonal Anti-C4A-Antikörper wurde für WB und IHC (p) validiert. Er ist geeignet, C4A in Proben von Human zu detektieren.

Kurzübersicht für C4A Antikörper (N-Term) (ABIN7466047)

Target: C4A (C4a) (Complement Fragment C4a (C4a))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser C4A Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails anti-C4A Antikörper

Bindungsspezifität: N-Term

Kreuzreaktivität: Human

Aufreinigung: Purified by antigen-affinity chromatography.

Immunogen: Recombinant protein encompassing a sequence within the N-terminus region of human C4. The exact sequence is proprietary.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB: 1:500-1:3000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Kommentare:

Positive Control: HepG2

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.52 mg/mL

Buffer: 0.1M Tris-Glycine ( pH 7), 20 % Glycerol, 0.01 % Thimerosal

Konservierungsmittel: Thimerosal (Merthiolate)

Vorsichtsmaßnahmen: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Details zu C4A

Target: C4A (C4a) (Complement Fragment C4a (C4a))

Andere Bezeichnung: complement component 4A (Rodgers blood group)

Hintergrund: C4 antibody , C4A2 antibody , C4A3 antibody , C4A4 antibody , C4A6 antibody , C4S antibody , CO4 antibody , CPAMD2 antibody , MGC164979 antibody , RG antibody , C4A antibody , C3 and PZP-like alpha-2-macroglobulin domain-containing protein 2 antibody , C4A anaphylatoxin antibody , acidic C4 antibody , acidic complement C4 antibody , Rodgers form of C4 antibody , complement C4-A antibody , complement component 4A (Rodgers blood group) antibody,This gene encodes the acidic form of complement factor 4, part of the classical activation pathway. The protein is expressed as a single chain precursor which is proteolytically cleaved into a trimer of alpha, beta, and gamma chains prior to secretion. The trimer provides a surface for interaction between the antigen-antibody complex and other complement components. The alpha chain may be cleaved to release C4 anaphylatoxin, a mediator of local inflammation. Deficiency of this protein is associated with systemic lupus erythematosus and type I diabetes mellitus. This gene localizes to the major histocompatibility complex (MHC) class III region on chromosome 6. Varying haplotypes of this gene cluster exist, such that individuals may have 1, 2, or 3 copies of this gene. [provided by RefSeq]

Molekulargewicht: 193 kDa

Gen-ID: 720

Pathways: Komplementsystem