RFC4 Antikörper

Produktnummer ABIN7465204

Der Maus Monoklonal Anti-RFC4-Antikörper wurde für WB, IF und ICC validiert. Er ist geeignet, RFC4 in Proben von Human zu detektieren.

Kurzübersicht für RFC4 Antikörper (ABIN7465204)

Target: RFC4 (Replication Factor C (Activator 1) 4, 37kDa (RFC4))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser RFC4 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF), Immunocytochemistry (ICC)

Klon: 1320

Produktdetails anti-RFC4 Antikörper

Kreuzreaktivität: Human, Maus

Aufreinigung: Protein G purified

Immunogen: Recombinant protein encoding the full-length p37 subunit ofhuman RFC purified from E. coli.

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: WB: 1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Kommentare:

Positive Control: 293T , A431 , HeLa , HepG2

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS, No Preservative

Konservierungsmittel: Without preservative

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Details zu RFC4

Target: RFC4 (Replication Factor C (Activator 1) 4, 37kDa (RFC4))

Andere Bezeichnung: replication factor C subunit 4

Hintergrund: Replication factor C subunit 4 , A1 , RFC37,The elongation of primed DNA templates by DNA polymerase delta and DNA polymerase epsilon requires the accessory proteins proliferating cell nuclear antigen (PCNA) and replication factor C (RFC). RFC, also named activator 1, is a protein complex consisting of five distinct subunits of 140, 40, 38, 37, and 36 kD. This gene encodes the 37 kD subunit. This subunit forms a core complex with the 36 and 40 kDa subunits. The core complex possesses DNA-dependent ATPase activity, which was found to be stimulated by PCNA in an in vitro system. Alternatively spliced transcript variants encoding the same protein have been reported. [provided by RefSeq, Jul 2008]

Molekulargewicht: 40 kDa

Gen-ID: 5984

UniProt: P35249

Pathways: Telomere Maintenance, DNA Reparatur, DNA Replication, Synthesis of DNA