TINF2 Antikörper

Produktnummer ABIN7464645

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch TINF2 in WB. Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für TINF2 Antikörper (ABIN7464645)

Target: TINF2 (TIN2) (TERF1 Interacting Nuclear Factor 2 (TIN2))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TINF2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-TINF2 Antikörper

Kreuzreaktivität: Human

Aufreinigung: Purified by antigen-affinity chromatography.

Immunogen: Full length human TIN2 Recombinant protein.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB: 1:500-1:3000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Kommentare:

Positive Control: IMR32 nuclear extract

Validation: Orthogonal

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: 1XPBS ( pH 7), 1 % BSA, 20 % Glycerol, 0.01 % Thimerosal

Konservierungsmittel: Thimerosal (Merthiolate)

Vorsichtsmaßnahmen: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Details zu TINF2

Target: TINF2 (TIN2) (TERF1 Interacting Nuclear Factor 2 (TIN2))

Andere Bezeichnung: TERF1 interacting nuclear factor 2

Hintergrund: TERF1 interacting nuclear factor 2 , DKCA3 , TIN2,This gene encodes one of the proteins of the shelterin, or telosome, complex which protects telomeres by allowing the cell to distinguish between telomeres and regions of DNA damage. The protein encoded by this gene is a critical part of shelterin, it interacts with the three DNA-binding proteins of the shelterin complex, and it is important for assembly of the complex. Mutations in this gene cause dyskeratosis congenita (DKC), an inherited bone marrow failure syndrome. [provided by RefSeq]

Molekulargewicht: 50 kDa

Gen-ID: 26277

UniProt: Q9BSI4

Pathways: Zellzyklus, Telomere Maintenance, Regulation of Carbohydrate Metabolic Process