PREX1 Antikörper

Produktnummer ABIN7464629

Produktdetails anti-PREX1 Antikörper

Target: PREX1 (Phosphatidylinositol-3,4,5-Trisphosphate-Dependent Rac Exchange Factor 1 (PREX1))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PREX1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Kreuzreaktivität: Human

Aufreinigung: Purified by antigen-affinity chromatography.

Immunogen: Recombinant protein encompassing a sequence within the center region of human PREX1. The exact sequence is proprietary.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB: 1:1000-1:10000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Kommentare:

Positive Control: human PREX1-transfected 293T cells

Validation: Overexpression

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: 1XPBS ( pH 7), 20 % Glycerol, 0.01 % Thimerosal

Konservierungsmittel: Thimerosal (Merthiolate)

Vorsichtsmaßnahmen: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Details zu PREX1

Target: PREX1 (Phosphatidylinositol-3,4,5-Trisphosphate-Dependent Rac Exchange Factor 1 (PREX1))

Andere Bezeichnung: phosphatidylinositol-3,4,5-trisphosphate dependent Rac exchange factor 1 (PREX1 Produkte)

Synonyme: MGC68772 antikoerper, P-REX1 antikoerper, G630042G04 antikoerper, Setd6 antikoerper, RGD1306534 antikoerper, phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 1 L homeolog antikoerper, phosphatidylinositol-3,4,5-trisphosphate dependent Rac exchange factor 1 antikoerper, phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 1 antikoerper, prex1.L antikoerper, PREX1 antikoerper, prex1 antikoerper, Prex1 antikoerper

Hintergrund: Phosphatidylinositol-3,4,5-trisphosphate dependent Rac exchange factor 1 , P-REX1,The protein encoded by this gene acts as a guanine nucleotide exchange factor for the RHO family of small GTP-binding proteins (RACs). It has been shown to bind to and activate RAC1 by exchanging bound GDP for free GTP. The encoded protein, which is found mainly in the cytoplasm, is activated by phosphatidylinositol-3,4,5-trisphosphate and the beta-gamma subunits of heterotrimeric G proteins. [provided by RefSeq]

Molekulargewicht: 186 kDa

Gen-ID: 57580

UniProt: Q8TCU6

Pathways: Regulation of Actin Filament Polymerization