UNG Antikörper

Produktnummer ABIN7464537

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch UNG in WB, IF, ICC und MA. Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für UNG Antikörper (ABIN7464537)

Target: UNG (Uracil-DNA Glycosylase (UNG))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser UNG Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF), Immunocytochemistry (ICC), Multiplex Assay (MA)

Güteklasse: KO Validated

Produktdetails anti-UNG Antikörper

Kreuzreaktivität: Human

Aufreinigung: Purified by antigen-affinity chromatography.

Immunogen: Recombinant protein encompassing a sequence within the center region of human UNG. The exact sequence is proprietary.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Kommentare:

Positive Control: HeLa

Validation: KO/KD

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.71 mg/mL

Buffer: 0.1M Tris-Glycine ( pH 7), 20 % Glycerol, 0.01 % Thimerosal

Konservierungsmittel: Thimerosal (Merthiolate)

Vorsichtsmaßnahmen: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Details zu UNG

Target: UNG (Uracil-DNA Glycosylase (UNG))

Andere Bezeichnung: uracil DNA glycosylase

Hintergrund: Uracil DNA glycosylase , DGU , HIGM4 , HIGM5 , UDG , UNG1 , UNG15 , UNG2,This gene encodes one of several uracil-DNA glycosylases. One important function of uracil-DNA glycosylases is to prevent mutagenesis by eliminating uracil from DNA molecules by cleaving the N-glycosylic bond and initiating the base-excision repair (BER) pathway. Uracil bases occur from cytosine deamination or misincorporation of dUMP residues. Alternative promoter usage and splicing of this gene leads to two different isoforms: the mitochondrial UNG1 and the nuclear UNG2. [provided by RefSeq]

Molekulargewicht: 35 kDa

Gen-ID: 7374

UniProt: P13051

Pathways: DNA Reparatur, Production of Molecular Mediator of Immune Response