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GCLM Antikörper (N-Term)

Der Kaninchen Polyklonal Anti-GCLM-Antikörper wurde für WB, IF, ICC und IHC (p) validiert. Er ist geeignet, GCLM in Proben von Human zu detektieren.
Produktnummer ABIN7464409

Kurzübersicht für GCLM Antikörper (N-Term) (ABIN7464409)

Target

Alle GCLM Antikörper anzeigen
GCLM (Glutamate-Cysteine Ligase, Modifier Subunit (GCLM))

Reaktivität

  • 63
  • 37
  • 30
  • 4
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
Human

Wirt

  • 61
  • 8
Kaninchen

Klonalität

  • 50
  • 19
Polyklonal

Konjugat

  • 40
  • 4
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 2
  • 1
  • 1
Dieser GCLM Antikörper ist unkonjugiert

Applikation

  • 45
  • 33
  • 25
  • 17
  • 15
  • 13
  • 13
  • 7
  • 2
  • 2
  • 1
  • 1
  • 1
Western Blotting (WB), Immunofluorescence (IF), Immunocytochemistry (ICC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Güteklasse

KO Validated
  • Bindungsspezifität

    • 12
    • 8
    • 7
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term

    Kreuzreaktivität

    Human

    Aufreinigung

    Purified by antigen-affinity chromatography.

    Immunogen

    Carrier-protein conjugated synthetic peptide encompassing a sequence within the N-terminus region of human GCLM. The exact sequence is proprietary.

    Isotyp

    IgG
  • Applikationshinweise

    WB: 1:1000-1:10000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

    Kommentare

    Positive Control: H1299 , HeLa

    Validation: KO/KD

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Konzentration

    1 mg/mL

    Buffer

    0.1M Tris-Glycine ( pH 7), 10 % Glycerol, 0.01 % Thimerosal

    Konservierungsmittel

    Thimerosal (Merthiolate)

    Vorsichtsmaßnahmen

    This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Lagerung

    4 °C,-20 °C

    Informationen zur Lagerung

    Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • Target

    GCLM (Glutamate-Cysteine Ligase, Modifier Subunit (GCLM))

    Andere Bezeichnung

    glutamate-cysteine ligase modifier subunit

    Hintergrund

    Glutamate-cysteine ligase modifier subunit , GLCLR,Glutamate-cysteine ligase, also known as gamma-glutamylcysteine synthetase, is the first rate limiting enzyme of glutathione synthesis. The enzyme consists of two subunits, a heavy catalytic subunit and a light regulatory subunit. Gamma glutamylcysteine synthetase deficiency has been implicated in some forms of hemolytic anemia. [provided by RefSeq]

    Molekulargewicht

    31 kDa

    Gen-ID

    2730

    UniProt

    P48507
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