HDAC2 Antikörper (C-Term)

Produktnummer ABIN7464379

Der Kaninchen Polyklonal Anti-HDAC2-Antikörper wurde für WB, IF, IP, IHC (p), ICC und ChIP validiert. Er ist geeignet, HDAC2 in Proben von Human zu detektieren.

Kurzübersicht für HDAC2 Antikörper (C-Term) (ABIN7464379)

Target: HDAC2 (Histone Deacetylase 2 (HDAC2))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser HDAC2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF), Immunoprecipitation (IP), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC), Chromatin Immunoprecipitation (ChIP)

Güteklasse: KO Validated

Produktdetails anti-HDAC2 Antikörper

Bindungsspezifität: C-Term

Spezifität: Knockdown/Knockout validation was supported by customer review data.

Kreuzreaktivität: Human, Maus, Ratte, Xenopus tropicalis

Aufreinigung: Purified by antigen-affinity chromatography.

Immunogen: Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human HDAC2. The exact sequence is proprietary.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. IP: 1:100-1:500. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Kommentare:

Positive Control: C2C12 , Rat2

Validation: KO/KD

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1.16 mg/mL

Buffer: 1XPBS ( pH 7), 20 % Glycerol, 0.025 % ProClin 300

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Details zu HDAC2

Target: HDAC2 (Histone Deacetylase 2 (HDAC2))

Andere Bezeichnung: histone deacetylase 2

Hintergrund: Histone deacetylase 2 , HD2 , KDAC2 , RPD3 , YAF1,This gene product belongs to the histone deacetylase family. Histone deacetylases act via the formation of large multiprotein complexes and are responsible for the deacetylation of lysine residues on the N-terminal region of the core histones (H2A, H2B, H3 and H4). This protein also forms transcriptional repressor complexes by associating with many different proteins, including YY1, a mammalian zinc-finger transcription factor. Thus it plays an important role in transcriptional regulation, cell cycle progression and developmental events. [provided by RefSeq]

Molekulargewicht: 55 kDa

Gen-ID: 3066

UniProt: Q92769

Pathways: Neurotrophin Signalübertragung, Regulation of Muscle Cell Differentiation, Negative Regulation of intrinsic apoptotic Signaling, SARS-CoV-2 Protein Interaktom, Phosphorylierungen bei SARS-CoV-2 Infektion