NLRP3 Antikörper (Cy5)
Kurzübersicht für NLRP3 Antikörper (Cy5) (ABIN719490)
Target
Alle NLRP3 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
-
-
Kreuzreaktivität
- Hund, Human, Maus, Ratte
-
Aufreinigung
- Purified by Protein A.
-
Immunogen
- KLH conjugated synthetic peptide derived from human Cryopyrin
-
Isotyp
- IgG
-
-
anti-NLR Family, Pyrin Domain Containing 3 (NLRP3) (AA 1-93), (Pyrin Domain) antibody
NLRP3 Reaktivität: Human, Maus WB, IHC, IF, IP Wirt: Maus Monoclonal Cryo-2 unconjugated
anti-NLR Family, Pyrin Domain Containing 3 (NLRP3) (AA 15-120) antibodyNLRP3 Reaktivität: Human, Maus, Ratte, Hund WB, ELISA, IHC (p), FACS, ICC, IHC (fro), IF (p), IF (cc) Wirt: Kaninchen Polyclonal unconjugated
anti-NLR Family, Pyrin Domain Containing 3 (NLRP3) (AA 671-1033) antibodyNLRP3 Reaktivität: Maus WB Wirt: Kaninchen Polyclonal unconjugated
anti-NLR Family, Pyrin Domain Containing 3 (NLRP3) (C-Term) antibodyVerified NLRP3 Reaktivität: Human ELISA, IHC, IF, FACS Wirt: Ziege Polyclonal unconjugated
anti-NLR Family, Pyrin Domain Containing 3 (NLRP3) (C-Term) antibodyNLRP3 Reaktivität: Human WB, IHC, IF Wirt: Kaninchen Polyclonal unconjugated
anti-NLR Family, Pyrin Domain Containing 3 (NLRP3) (N-Term) antibodyNLRP3 Reaktivität: Human, Maus, Ratte WB, IF, IHC (p), FACS, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-NLR Family, Pyrin Domain Containing 3 (NLRP3) (AA 12-31), (N-Term) antibodyNLRP3 Reaktivität: Human, Maus, Ratte WB, IHC, FACS Wirt: Kaninchen Polyclonal unconjugated
anti-NLR Family, Pyrin Domain Containing 3 (NLRP3) (AA 65-91), (N-Term) antibodyNLRP3 Reaktivität: Human WB, IHC (p) Wirt: Kaninchen Polyclonal RB22404 unconjugated
anti-NLR Family, Pyrin Domain Containing 3 (NLRP3) (AA 158-207) antibodyNLRP3 Reaktivität: Human, Hund, Affe WB, IHC, IHC (p) Wirt: Kaninchen Polyclonal unconjugated
anti-NLR Family, Pyrin Domain Containing 3 (NLRP3) (AA 30-102) antibodyNLRP3 Reaktivität: Human ELISA, IHC, IF Wirt: Kaninchen Polyclonal unconjugated
-
-
Applikationshinweise
-
IF(IHC-P)(1:100-500)
Optimal working dilution should be determined by the investigator. -
Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
-
-
Format
- Liquid
-
Konzentration
- 1 μg/μL
-
Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
-
Konservierungsmittel
- Sodium azide
-
Vorsichtsmaßnahmen
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Lagerung
- -20 °C
-
Informationen zur Lagerung
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
-
Haltbarkeit
- 12 months
-
-
- NLRP3 (NLR Family, Pyrin Domain Containing 3 (NLRP3))
-
Andere Bezeichnung
- Cryopyrin
-
Hintergrund
-
Synonyms: NACHT, LRR and PYD domains-containing protein 3, Angiotensin/vasopressin receptor AII/AVP-like, Caterpiller protein 1.1, CLR1.1, Cold autoinflammatory syndrome 1 protein, Cryopyrin, PYRIN-containing APAF1-like protein 1, NLRP3, C1orf7, CIAS1, NALP3, PYPAF1
Background: May function as an inducer of apoptosis. Interacts selectively with ASC and this complex may function as an upstream activator of NF-kappa-B signaling. Inhibits TNF-alpha induced activation and nuclear translocation of RELA/NF-KB p65. Also inhibits transcriptional activity of RELA. Activates caspase-1 in response to a number of triggers including bacterial or viral infection which leads to processing and release of IL1B and IL18.
-
Molekulargewicht
- 118kDa
-
Gen-ID
- 114548
-
Pathways
- Cellular Response to Molecule of Bacterial Origin, Positive Regulation of Endopeptidase Activity, Inflammasome
Target
-
