Nibrin Antikörper

Produktnummer ABIN7464244

Der Maus Monoklonal Anti-Nibrin Antikörper wurde für WB, IF, ICC und IP validiert. Er ist geeignet, Nibrin in Proben von Human zu detektieren.

Kurzübersicht für Nibrin Antikörper (ABIN7464244)

Target: Nibrin (NBN)

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser Nibrin Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF), Immunocytochemistry (ICC), Immunoprecipitation (IP)

Güteklasse: KO Validated

Klon: 1C3

Produktdetails anti-Nibrin Antikörper

Kreuzreaktivität: Human, Maus

Aufreinigung: Protein G purified

Immunogen: The complete coding region of the human p95/NBS1 expressed in E. coli.

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: WB: 1:500-1:3000. ICC/IF: 1:100. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Kommentare:

Positive Control: 293T , MCF7 , HeLa , Raji

Validation: KO/KD, Orthogonal

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: 1XPBS ( pH 7), 20 % Glycerol, No Preservative

Konservierungsmittel: Without preservative

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Details zu Nibrin

Target: Nibrin (NBN)

Andere Bezeichnung: nibrin

Hintergrund: Nibrin , AT-V1 , AT-V2 , ATV , NBS , NBS1 , P95,Mutations in this gene are associated with Nijmegen breakage syndrome, an autosomal recessive chromosomal instability syndrome characterized by microcephaly, growth retardation, immunodeficiency, and cancer predisposition. The encoded protein is a member of the MRE11/RAD50 double-strand break repair complex which consists of 5 proteins. This gene product is thought to be involved in DNA double-strand break repair and DNA damage-induced checkpoint activation. [provided by RefSeq, Jul 2008]

Molekulargewicht: 85 kDa

Gen-ID: 4683

UniProt: O60934

Pathways: DNA Reparatur, Production of Molecular Mediator of Immune Response