HMGA1 Antikörper (N-Term)

Produktnummer ABIN7464188

Dieses Anti-HMGA1-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von HMGA1 in WB, ICC und IF. Geeignet für Human.

Kurzübersicht für HMGA1 Antikörper (N-Term) (ABIN7464188)

Target: HMGA1 (High Mobility Group AT-Hook 1 (HMGA1))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser HMGA1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunocytochemistry (ICC), Immunofluorescence (IF)

Güteklasse: KO Validated

Produktdetails anti-HMGA1 Antikörper

Bindungsspezifität: N-Term

Kreuzreaktivität: Human

Aufreinigung: Purified by antigen-affinity chromatography.

Immunogen: Recombinant protein encompassing a sequence within the N-terminus region of human HMGA1. The exact sequence is proprietary.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Kommentare:

Positive Control: 293T , A431 , HeLa , HepG2

Validation: KO/KD

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.87 mg/mL

Buffer: 1XPBS ( pH 7), 20 % Glycerol, 0.025 % ProClin 300

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Details zu HMGA1

Target: HMGA1 (High Mobility Group AT-Hook 1 (HMGA1))

Andere Bezeichnung: high mobility group AT-hook 1

Hintergrund: High mobility group AT-hook 1 , HMG-R , HMGA1A , HMGIY,This gene encodes a non-histone protein involved in many cellular processes, including regulation of inducible gene transcription, integration of retroviruses into chromosomes, and the metastatic progression of cancer cells. The encoded protein preferentially binds to the minor groove of A+T-rich regions in double-stranded DNA. It has little secondary structure in solution but assumes distinct conformations when bound to substrates such as DNA or other proteins. The encoded protein is frequently acetylated and is found in the nucleus. At least seven transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq]

Molekulargewicht: 12 kDa

Gen-ID: 3159

UniProt: P17096

Pathways: Nuclear Hormone Receptor Binding, Autophagie