CHD1L Antikörper (C-Term)
Kurzübersicht für CHD1L Antikörper (C-Term) (ABIN7464179)
Target
Alle CHD1L Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Güteklasse
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Bindungsspezifität
- C-Term
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Kreuzreaktivität
- Human
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Aufreinigung
- Purified by antigen-affinity chromatography.
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Immunogen
- Recombinant protein encompassing a sequence within the C-terminus region of human CHD1L. The exact sequence is proprietary.
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Isotyp
- IgG
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Applikationshinweise
- WB: 1:5000-1:20000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
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Kommentare
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Positive Control: 293T , A431 , HeLa , HepG2
Validation: KO/KD
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 1 mg/mL
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Buffer
- 1XPBS ( pH 7), 20 % Glycerol, 0.025 % ProClin 300
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Konservierungsmittel
- ProClin
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Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- 4 °C,-20 °C
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Informationen zur Lagerung
- Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
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- CHD1L (Chromodomain Helicase DNA Binding Protein 1-Like (CHD1L))
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Andere Bezeichnung
- chromodomain helicase DNA binding protein 1 like
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Hintergrund
- Chromodomain helicase DNA binding protein 1 like , ALC1 , CHDL,In response to DNA strand breaks, chromatin adopts a relaxed structure due to the addition of poly(ADP-ribose) (PAR) to chromatin proteins by PARP enzymes (see PARP1, MIM 173870), and this relaxation facilitates the repair of DNA damage. CHD1L interacts with PAR and has a role in chromatin relaxation following DNA damage (Ahel et al., 2009 [PubMed 19661379]).[supplied by OMIM]
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Molekulargewicht
- 101 kDa
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Gen-ID
- 9557
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UniProt
- Q86WJ1
Target
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