IL2 Receptor beta Antikörper

Produktnummer ABIN7457874

Dieses Ratte Monoklonal-Antikörper erkennt spezifisch IL2 Receptor beta in FACS. Er zeigt eine Reaktivität gegenüber Maus.

Kurzübersicht für IL2 Receptor beta Antikörper (ABIN7457874)

Target: IL2 Receptor beta (IL2RB) (Interleukin 2 Receptor, beta (IL2RB))

Reaktivität: Maus

Wirt: Ratte

Klonalität: Monoklonal

Konjugat: Dieser IL2 Receptor beta Antikörper ist unkonjugiert

Applikation: Flow Cytometry (FACS)

Klon: 5H4

Produktdetails anti-IL2 Receptor beta Antikörper

Aufreinigung: Purified

Sterilität: 0.2 μm filtered

Endotoxin-Niveau: Low Endotoxin: Endotoxin level is < 2 EU/mg as Determined by LAL gel clotting assay.

Isotyp: IgG2a, kappa

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

Matching Isotype Control: AF/LE Purified Rat IgG2a, κ Isotype Control (ABIN7469836)

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0.5 mg/mL

Buffer: PBS, pH 7.2. Azide Free (AF)/Low Endotoxin (LE)

Konservierungsmittel: Azide free

Lagerung: 4 °C

Informationen zur Lagerung: Store at 2~8°C. Do not freeze.

Details zu IL2 Receptor beta

Target: IL2 Receptor beta (IL2RB) (Interleukin 2 Receptor, beta (IL2RB))

Andere Bezeichnung: CD122

Hintergrund: Interleukin-2 receptor subunit beta,Il2rb,IL-2 receptor subunit beta, IL-2R subunit beta,IL-2RB,High affinity IL-2 receptor subunit beta,p70-75,CD122,CD122 is a 70-75 kD IL-2 receptor β chain also known as IL-2Rβ, which is also shared by the IL-15 receptor. It is constitutively expressed by NK cells and at lower levels by T cells, B cells, monocytes, and macrophages. The IL-2Rβ chain can combine with either the common γ subunit (γc, CD132) alone or with the γc subunit and the IL-2Rα subunit (CD25) to generate intermediate or high affinity IL-2 receptor complexes, respectively. CD122 expression levels can be upregulated by activation. The 5H4 antibody does not block IL-2 binding to the IL-2 receptor. CD122 is expressed on murine, but not human, CD8+ Tregs involved in the maintenance of T cell homeostasis.

Gen-ID: 16185

UniProt: P16297

Pathways: JAK-STAT Signalweg, Growth Factor Binding