CD80 Antikörper
Kurzübersicht für CD80 Antikörper (ABIN7457845)
Target
Alle CD80 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Aufreinigung
- Purified
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Sterilität
- 0.2 μm filtered
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Endotoxin-Niveau
- Low Endotoxin: Endotoxin level is < 2 EU/mg as Determined by LAL gel clotting assay.
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Isotyp
- IgG
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Applikationshinweise
- Optimal working dilution should be determined by the investigator.
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Kommentare
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Matching Isotype Control: AF/LE Purified Armenian Hamster IgG Isotype Control (ABIN7469872)
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Konzentration
- 0.5 mg/mL
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Buffer
- PBS, pH 7.2. Azide Free (AF)/Low Endotoxin (LE)
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Konservierungsmittel
- Azide free
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Lagerung
- 4 °C
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Informationen zur Lagerung
- Store at 2~8°C. Do not freeze.
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- CD80
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Andere Bezeichnung
- CD80
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Hintergrund
- T-lymphocyte activation antigen CD80,Cd80,Activation B7-1 antigen,B7,CD80 is a 60 kD highly glycosylated protein. It is a member of the Ig superfamily and is also known as B7-1, B7, and Ly-53. CD80 is constitutively expressed on dendritic cells and monocytes/macrophages, and inducibly expressed on activated B and T cells. The ligation of CD28 on T cells with CD80 and CD86 (B7-2) on antigen presenting cells (such as dendritic cells, macrophages, and B cells) elicits co-stimulation of T cells resulting in enhanced cell activation, proliferation, and cytokine production. CD80 appears to be expressed later in the immune response than CD86. CD80 can also bind to CD152, also known as CTLA-4, to deliver an inhibitory signal to T cells.
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Gen-ID
- 12519
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UniProt
- Q00609
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Pathways
- T-Zell Rezeptor Signalweg, Fc-epsilon Rezeptor Signalübertragung, EGFR Signaling Pathway, Neurotrophin Signalübertragung, Positive Regulation of Immune Effector Process, Cancer Immune Checkpoints
Target
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