CD80 Antikörper (PE-Cy7)

Produktnummer ABIN7457636

Dieses Anti-CD80-Antikörper ist ein Maus Monoklonal-Antikörper zur Detektion von CD80 in FACS. Geeignet für Human.

Kurzübersicht für CD80 Antikörper (PE-Cy7) (ABIN7457636)

Target: CD80

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser CD80 Antikörper ist konjugiert mit PE-Cy7

Applikation: Flow Cytometry (FACS)

Klon: 2D10

Produktdetails anti-CD80 Antikörper (PE-Cy7)

Isotyp: IgG1, kappa

Anwendungsinformationen

Applikationshinweise: The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.

Kommentare:

Matching Isotype Control: PE/Cyanine7 Mouse IgG1, κ Isotype Control (ABIN7469764)

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: PBS with 0.05 % Proclin300, 1 % BSA

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Informationen zur Lagerung: Store at 2~8°C and protected from prolonged exposure to light. Do not freeze.

Details zu CD80

Target: CD80

Andere Bezeichnung: CD80

Hintergrund: T-lymphocyte activation antigen CD80,B7-1, B7, BB1,CD80 is a 60 kD highly glycosylated protein. It is a member of the Ig superfamily and is also known as B7-1, B7, and Ly-53. CD80 is constitutively expressed on dendritic cells and monocytes/macrophages, and inducibly expressed on activated B and T cells. The ligation of CD28 on T cells with CD80 and CD86 (B7-2) on antigen presenting cells (such as dendritic cells, macrophages, and B cells) elicits co-stimulation of T cells resulting in enhanced cell activation, proliferation, and cytokine production. CD80 appears to be expressed later in the immune response than CD86. CD80 can also bind to CD152, also known as CTLA-4, to deliver an inhibitory signal to T cells.

Gen-ID: 941

UniProt: P33681

Pathways: T-Zell Rezeptor Signalweg, Fc-epsilon Rezeptor Signalübertragung, EGFR Signaling Pathway, Neurotrophin Signalübertragung, Positive Regulation of Immune Effector Process, Cancer Immune Checkpoints