IL2 Receptor beta Antikörper (PE)

Produktnummer ABIN7457087

Dieses Anti-IL2 Receptor beta-Antikörper ist ein Maus Monoklonal-Antikörper zur Detektion von IL2 Receptor beta in FACS. Geeignet für Human.

Kurzübersicht für IL2 Receptor beta Antikörper (PE) (ABIN7457087)

Target: IL2 Receptor beta (IL2RB) (Interleukin 2 Receptor, beta (IL2RB))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser IL2 Receptor beta Antikörper ist konjugiert mit PE

Applikation: Flow Cytometry (FACS)

Klon: TU27

Produktdetails anti-IL2 Receptor beta Antikörper (PE)

Isotyp: IgG1, kappa

Anwendungsinformationen

Applikationshinweise: The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.

Kommentare:

Matching Isotype Control: PE Mouse IgG1, κ Isotype Control (ABIN7469761)

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: PBS with 0.05 % Proclin300, 1 % BSA

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Informationen zur Lagerung: Store at 2~8°C and protected from prolonged exposure to light. Do not freeze.

Details zu IL2 Receptor beta

Target: IL2 Receptor beta (IL2RB) (Interleukin 2 Receptor, beta (IL2RB))

Andere Bezeichnung: CD122/IL-2RB

Hintergrund: Interleukin-2 receptor subunit beta,IL-2RB,p75,CD122,IL-2Rβ,CD122 is a 70-75 kD type I transmembrane glycoprotein and member of the Ig superfamily. It is IL-2 receptor β chain also known as IL-2Rβ, which is also shared by the IL-15 receptor. CD122 is constitutively expressed by NK cells and at lower levels by a subset of T cells. Its expression is upregulated upon activation. The IL-2Rβ chain can combine with either the common γ subunit (γc, CD132) alone or with the γc subunit and the IL-2Rα subunit (CD25) to generate intermediate or high affinity IL-2 receptor complexes, respectively. CD122 expression levels can be upregulated by activation.

Gen-ID: 3560

UniProt: P14784

Pathways: JAK-STAT Signalweg, Growth Factor Binding