Endoglin Antikörper (FITC)

Produktnummer ABIN7456907

Dieses Anti-Endoglin-Antikörper ist ein Ratte Monoklonal-Antikörper zur Detektion von Endoglin in FACS. Geeignet für Maus.

Kurzübersicht für Endoglin Antikörper (FITC) (ABIN7456907)

Target: Endoglin (ENG)

Reaktivität: Maus

Wirt: Ratte

Klonalität: Monoklonal

Konjugat: Dieser Endoglin Antikörper ist konjugiert mit FITC

Applikation: Flow Cytometry (FACS)

Klon: MJ7-18

Produktdetails anti-Endoglin Antikörper (FITC)

Isotyp: IgG2a, kappa

Anwendungsinformationen

Applikationshinweise: The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.

Kommentare:

Matching Isotype Control: FITC Rat IgG2a, κ Isotype Control (ABIN7469828)

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: PBS with 0.05 % Proclin300, 1 % BSA

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Informationen zur Lagerung: Store at 2~8°C and protected from prolonged exposure to light. Do not freeze.

Details zu Endoglin

Target: Endoglin (ENG)

Andere Bezeichnung: CD105

Hintergrund: Endoglin,END,Eng,CD105 is a 90 kD homodimeric type I integral membrane glycoprotein, also known as endoglin. It is expressed on endothelial cells (especially on angiogenic endothelial cells) and upregulated by hypoxia, activated monocytes, macrophages, bone marrow stromal cells, and some cytotrophoblasts. CD105 is a receptor for TGF-β1, TGF-β3 and modulates TGF-β signaling by interacting with TGF-β receptors I and/or II. CD105 also binds other growth factors such as actvin A, BMP-2, and BMP-7. CD105 has been show to be a useful marker for identifying proliferating endothelium involved in tumor angiogenesis and can be used for tumor imaging and prognosis, and has therapeutic potential for some solid tumors and other angiogenic diseases.

Gen-ID: 13805

UniProt: Q63961