IL-21 Antikörper (APC)

Produktnummer ABIN7456559

Dieses Anti-IL-21-Antikörper ist ein Maus Monoklonal-Antikörper zur Detektion von IL-21 in ICFC. Geeignet für Human.

Kurzübersicht für IL-21 Antikörper (APC) (ABIN7456559)

Target: IL-21 (IL21) (Interleukin 21 (IL21))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser IL-21 Antikörper ist konjugiert mit APC

Applikation: Intracellular Flow Cytometry (ICFC)

Klon: 3A3-N2

Produktdetails anti-IL-21 Antikörper (APC)

Isotyp: IgG1, kappa

Anwendungsinformationen

Applikationshinweise: The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.

Kommentare:

Matching Isotype Control: APC Mouse IgG1, κ Isotype Control (ABIN7469762)

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: PBS with 0.05 % Proclin300, 1 % BSA

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Informationen zur Lagerung: Store at 2~8°C and protected from prolonged exposure to light. Do not freeze.

Details zu IL-21

Target: IL-21 (IL21) (Interleukin 21 (IL21))

Andere Bezeichnung: IL-21

Hintergrund: Interleukin-21,IL-21,Za11,Interleukin 21 (IL-21) is a potent immunomodulatory cytokine mainly produced by NKT and CD4+ T-cells, particularly the inflammatory Th17 subset, and has pleiotropic effects on both innate and adaptive immune responses. These actions include positive effects such as enhancing proliferation of NK cells and cytotoxic T cells, and inhibitory effects on the antigen-presenting function of dendritic cells. It can also be proapoptotic for B cells and NK cells. Studies have shown that IL-21 is also an autocrine cytokine that potently induces Th17 differentiation, suppresses Foxp3 expression, and serves as a target for treating inflammatory diseases.

Gen-ID: 59067

UniProt: Q9HBE4

Pathways: JAK-STAT Signalweg, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response