TNFSF15 Antikörper

Produktnummer ABIN7490770

Dieses Kaninchen Chimeric-Antikörper erkennt spezifisch TNFSF15 in FACS. Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für TNFSF15 Antikörper (ABIN7490770)

Target: TNFSF15 (Tumor Necrosis Factor (Ligand) Superfamily, Member 15 (TNFSF15))

Fragment: Fc fragment

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Chimeric

Konjugat: Dieser TNFSF15 Antikörper ist unkonjugiert

Applikation: Flow Cytometry (FACS)

Produktdetails anti-TNFSF15 Antikörper

Produktmerkmale: Rabbit/Human Fc chimeric IgG1

Aufreinigung: Purified from cell culture supernatant by affinity chromatography

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: Flow Cyt  1:100

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

Haltbarkeit: 12 months

Details zu TNFSF15

Target: TNFSF15 (Tumor Necrosis Factor (Ligand) Superfamily, Member 15 (TNFSF15))

Andere Bezeichnung: TNFSF15

Hintergrund: TL1, VEGI,
Description: The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This protein is abundantly expressed in endothelial cells, but is not expressed in either B or T cells. The expression of this protein is inducible by TNF and IL-1 alpha. This cytokine is a ligand for receptor TNFRSF25 and decoy receptor TNFRSF21/DR6. It can activate NF-kappaB and MAP kinases, and acts as an autocrine factor to induce apoptosis in endothelial cells. This cytokine is also found to inhibit endothelial cell proliferation, and thus may function as an angiogenesis inhibitor. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2011]

UniProt: O95150

Pathways: Positive Regulation of Endopeptidase Activity, Autophagie