PVRL4 Antikörper

Produktnummer ABIN7490714

Der Kaninchen Chimeric Anti-PVRL4 Antikörper wurde für FACS validiert. Er ist geeignet, PVRL4 in Proben von Human zu detektieren.

Kurzübersicht für PVRL4 Antikörper (ABIN7490714)

Target: PVRL4 (Poliovirus Receptor-Related 4 (PVRL4))

Fragment: Fc fragment

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Chimeric

Konjugat: Dieser PVRL4 Antikörper ist unkonjugiert

Applikation: Flow Cytometry (FACS)

Produktdetails anti-PVRL4 Antikörper

Produktmerkmale: Rabbit/Human Fc chimeric IgG1

Aufreinigung: Purified from cell culture supernatant by affinity chromatography

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: Flow Cyt  1:100

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

Haltbarkeit: 12 months

Details zu PVRL4

Target: PVRL4 (Poliovirus Receptor-Related 4 (PVRL4))

Andere Bezeichnung: NECTIN4

Hintergrund: EDSS1, LNIR, nectin-4, PRR4, PVRL4,
Description: This gene encodes a member of the nectin family. The encoded protein contains two immunoglobulin-like (Ig-like) C2-type domains and one Ig-like V-type domain. It is involved in cell adhesion through trans-homophilic and -heterophilic interactions. It is a single-pass type I membrane protein. The soluble form is produced by proteolytic cleavage at the cell surface by the metalloproteinase ADAM17/TACE. The secreted form is found in both breast tumor cell lines and breast tumor patients. Mutations in this gene are the cause of ectodermal dysplasia-syndactyly syndrome type 1, an autosomal recessive disorder. Alternatively spliced transcript variants have been found but the full-length nature of the variant has not been determined.

UniProt: Q96NY8

Pathways: Cell-Cell Junction Organization