PVRL4 Antikörper (AA 371-510)

Produktnummer ABIN7269433

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch PVRL4 in WB. Es zeigt Reaktivität gegenüber Proben von Human.

Kurzübersicht für PVRL4 Antikörper (AA 371-510) (ABIN7269433)

Target: PVRL4 (Poliovirus Receptor-Related 4 (PVRL4))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PVRL4 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-PVRL4 Antikörper

Bindungsspezifität: AA 371-510

Verwendungszweck: PVRL4 Rabbit pAb

Sequenz: MSRYHRRKAQ QMTQKYEEEL TLTRENSIRR LHSHHTDPRS QPEESVGLRA EGHPDSLKDN SSCSVMSEEP EGRSYSTLTT VREIETQTEL LSPGSGRAEE EEDQDEGIKQ AMNHFVQENG TLRAKPTGNG IYINGRGHLV

Kreuzreaktivität: Human, Maus, Ratte

Produktmerkmale: Polyclonal Antibodies

Aufreinigung: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 371-510 of human PVRL4 (NP_112178.2).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu PVRL4

Target: PVRL4 (Poliovirus Receptor-Related 4 (PVRL4))

Andere Bezeichnung: NECTIN4

Hintergrund: This gene encodes a member of the nectin family. The encoded protein contains two immunoglobulin-like (Ig-like) C2-type domains and one Ig-like V-type domain. It is involved in cell adhesion through trans-homophilic and -heterophilic interactions. It is a single-pass type I membrane protein. The soluble form is produced by proteolytic cleavage at the cell surface by the metalloproteinase ADAM17/TACE. The secreted form is found in both breast tumor cell lines and breast tumor patients. Mutations in this gene are the cause of ectodermal dysplasia-syndactyly syndrome type 1, an autosomal recessive disorder. Alternatively spliced transcript variants have been found but the full-length nature of the variant has not been determined.,NECTIN4,EDSS1,LNIR,PRR4,PVRL4,nectin-4,Cell Biology & Developmental Biology,Cell Adhesion,Tight Junctions,NECTIN4

Molekulargewicht: 24kDa/55kDa

Gen-ID: 81607

UniProt: Q96NY8

Pathways: Cell-Cell Junction Organization