BCL2L1 Antikörper

Produktnummer ABIN7490462

Dieses Kaninchen Monoklonal-Antikörper erkennt spezifisch BCL2L1 in ELISA und FACS. Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für BCL2L1 Antikörper (ABIN7490462)

Target: BCL2L1 (BCL2-Like 1 (BCL2L1))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Monoklonal

Konjugat: Dieser BCL2L1 Antikörper ist unkonjugiert

Applikation: ELISA, Flow Cytometry (FACS)

Produktdetails anti-BCL2L1 Antikörper

Produktmerkmale: Rabbit IgG

Aufreinigung: Purified from cell culture supernatant by affinity chromatography

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: ELISA 1:5000-10000, Flow Cyt  1:100

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

Haltbarkeit: 12 months

Details zu BCL2L1

Target: BCL2L1 (BCL2-Like 1 (BCL2L1))

Andere Bezeichnung: BCL2L1

Hintergrund: Bcl-X, BCL-XL/S, BCL2L, BCLX, PPP1R52,
Description: The protein encoded by this gene belongs to the BCL-2 protein family. BCL-2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. The proteins encoded by this gene are located at the outer mitochondrial membrane, and have been shown to regulate outer mitochondrial membrane channel (VDAC) opening. VDAC regulates mitochondrial membrane potential, and thus controls the production of reactive oxygen species and release of cytochrome C by mitochondria, both of which are the potent inducers of cell apoptosis. Alternative splicing results in multiple transcript variants encoding two different isoforms. The longer isoform acts as an apoptotic inhibitor and the shorter isoform acts as an apoptotic activator.

UniProt: Q07817

Pathways: Apoptose, Negative Regulation of intrinsic apoptotic Signaling