Rekombinanter beta Catenin Antikörper (AA 725-775)
Kurzübersicht für Rekombinanter beta Catenin Antikörper (AA 725-775) (ABIN7455205)
Target
Alle beta Catenin (CATNB) Antikörper anzeigenAntikörpertyp
Reaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Bindungsspezifität
- AA 725-775
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Verwendungszweck
- Rabbit anti-beta Catenin Recombinant Monoclonal Antibody [BLR086G]
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Immunogen
- between AA 725 and 775
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Isotyp
- IgG
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Applikationshinweise
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IHC-IF: 1:100 to 1:500. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.
IHC: 1:100 to 1:500. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.
IP: 20 μL/1 mg lysate
ICC: 1:100 to 1:500. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE cell sections.
WB: 17:40:00
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Konzentration
- 250 μg/mL
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Buffer
- Borate Buffered Saline (BBS) pH 8.2 with 0.1 % BSA and 0.09 % Sodium Azide
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- 4 °C
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Haltbarkeit
- 12 months
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- beta Catenin (CATNB) (Catenin, beta (CATNB))
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Andere Bezeichnung
- beta Catenin
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Hintergrund
- Background: beta Catenin plays an integral role in the Wnt signaling pathway and is critical to morphogenic signaling and body axis specification. Beta Catenin exists in complexes with cadherins, transmembrane proteins that mediate cell adhesion. When Wnt-signaling proteins bind their receptors, beta Catenin is stabilized and accumulates in the cell. Translocation of stabilized beta Catenin allows its association with transcription factors and the activation of specific gene expression.
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Gen-ID
- 1499
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NCBI Accession
- NP_001895
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UniProt
- P35222
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Pathways
- Peptide Hormone Metabolism
Target
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