Rekombinanter CD276 Antikörper (C-Term)

Produktnummer ABIN7455195

Dieses Kaninchen Monoklonal-Antikörper erkennt spezifisch CD276 in WB, FACS, IP, ICC, IF (p) und IHC (fp). Er zeigt eine Reaktivität gegenüber Human und Maus.

Kurzübersicht für Rekombinanter CD276 Antikörper (C-Term) (ABIN7455195)

Target: CD276

Antikörpertyp: Recombinant Antibody

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Monoklonal

Konjugat: Dieser CD276 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Flow Cytometry (FACS), Immunoprecipitation (IP), Immunocytochemistry (ICC), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))

Klon: BLR025F

Produktdetails anti-CD276 Antikörper

Bindungsspezifität: C-Term

Verwendungszweck: Rabbit anti-B7-H3/CD276 Recombinant Monoclonal Antibody [BLR025F]

Immunogen: between AA 500 to 534 (C-term)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise:

IHC-IF: 1:100 to 1:500. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.

IHC: 1:100 - 1:500. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.

IP: 20 μL/mg lysate

ICC: 1:100 - 1:500. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE cell sections.

WB: 17:40:00

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1000 μg/mL

Buffer: Borate Buffered Saline (BBS) pH 8.2 with 0.09 % Sodium Azide, BSA-Free

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Haltbarkeit: 12 months

Details zu CD276

Target: CD276

Andere Bezeichnung: B7-H3/CD276

Hintergrund: Background: CD276 may participate in the regulation of T-cell-mediated immune response. CD276 may play a protective role in tumor cells by inhibiting natural-killer mediated cell lysis as well as a role of marker for detection of neuroblastoma cells. It may also be involved in the development of acute and chronic transplant rejection and in the regulation of lymphocytic activity at mucosal surfaces and could also play a key role in providing the placenta and fetus with a suitable immunological environment throughout pregnancy [taken from the Universal Protein Resource (UniProt) Q5ZPR3].

Gen-ID: 80381

NCBI Accession: NP_001019907

UniProt: Q5ZPR3

Pathways: Cancer Immune Checkpoints