Rekombinanter Cadherin 5 Antikörper (AA 48-599)
Kurzübersicht für Rekombinanter Cadherin 5 Antikörper (AA 48-599) (ABIN7455190)
Target
Alle Cadherin 5 (CDH5) Antikörper anzeigenAntikörpertyp
Reaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Bindungsspezifität
- AA 48-599
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Verwendungszweck
- Rabbit anti-VE-Cadherin Recombinant Monoclonal Antibody [BLR091G]
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Immunogen
- residues 48-599 (ECD)
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Isotyp
- IgG
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Applikationshinweise
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IHC-IF: 1:100 to 1:500. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.
IHC: 1:100 to 1:500. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.
IP: 6 μL/1 mg lysate
ICC: 1:100 to 1:500. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE cell sections.
WB: 17:40:00
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Konzentration
- 1000 μg/mL
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Buffer
- Borate Buffered Saline (BBS) pH 8.2 with 0.09 % Sodium Azide, BSA-Free
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- 4 °C
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Haltbarkeit
- 12 months
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- Cadherin 5 (CDH5)
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Andere Bezeichnung
- VE-Cadherin
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Hintergrund
- Background: Cadherins are calcium-dependent cell adhesion proteins that preferentially interact with themselves in a homophilic manner in adjacent cells. VE-Cadherin, or Cadherin-5 plays an important role in endothelial cell biology through control of the cohesion and organization of the intercellular junctions. It associates with alpha-catenin forming a link to the cytoskeleton and acts in concert with KRIT1 and MPP5 to establish and maintain correct endothelial cell polarity and vascular lumen. [taken from the Universal Protein Resource (UniProt) P33151].
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Gen-ID
- 1003
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NCBI Accession
- NP_001786
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UniProt
- P33151
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Pathways
- Cell-Cell Junction Organization, Signaling Events mediated by VEGFR1 and VEGFR2
Target
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