Rekombinanter CD276 Antikörper (AA 29-465)

Produktnummer ABIN7455137

Dieses Anti-CD276-Antikörper ist ein Kaninchen Monoklonal-Antikörper zur Detektion von CD276 in WB, FACS, IP, ICC und IHC (fp). Geeignet für Human.

Kurzübersicht für Rekombinanter CD276 Antikörper (AA 29-465) (ABIN7455137)

Target: CD276

Antikörpertyp: Recombinant Antibody

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Monoklonal

Konjugat: Dieser CD276 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Flow Cytometry (FACS), Immunoprecipitation (IP), Immunocytochemistry (ICC), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))

Klon: BLR026F

Produktdetails anti-CD276 Antikörper

Bindungsspezifität: AA 29-465

Verwendungszweck: Rabbit anti-B7-H3/CD276 Recombinant Monoclonal Antibody [BLR026F]

Immunogen: residues 29-465 (ECD)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise:

IHC: 1:100 to 1:500. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.

IP: 3 μL/mg lysate

ICC: 1:100 to 1:500. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE cell sections.

WB: 17:40:00

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1000 μg/mL

Buffer: Borate Buffered Saline (BBS) pH 8.2 with 0.09 % Sodium Azide, BSA-Free

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Haltbarkeit: 12 months

Details zu CD276

Target: CD276

Andere Bezeichnung: B7-H3/CD276

Hintergrund: Background: CD276 may participate in the regulation of T-cell-mediated immune response. CD276 may play a protective role in tumor cells by inhibiting natural-killer mediated cell lysis as well as a role of marker for detection of neuroblastoma cells. It may also be involved in the development of acute and chronic transplant rejection and in the regulation of lymphocytic activity at mucosal surfaces and could also play a key role in providing the placenta and fetus with a suitable immunological environment throughout pregnancy [taken from the Universal Protein Resource (UniProt) Q5ZPR3].

Gen-ID: 80381

NCBI Accession: NP_001019907

UniProt: Q5ZPR3

Pathways: Cancer Immune Checkpoints