AIMP1 Antikörper (AA 262-312)

Produktnummer ABIN7455058

Der Kaninchen Polyklonal Anti-AIMP1-Antikörper wurde für WB, IP und IHC (fp) validiert. Er ist geeignet, AIMP1 in Proben von Human und Maus zu detektieren.

Kurzübersicht für AIMP1 Antikörper (AA 262-312) (ABIN7455058)

Target: AIMP1 (Aminoacyl tRNA Synthetase Complex-Interacting Multifunctional Protein 1 (AIMP1))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser AIMP1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))

Produktdetails anti-AIMP1 Antikörper

Bindungsspezifität: AA 262-312

Verwendungszweck: Rabbit anti-AIMP1/EMAPII/SCYE1 Antibody, Affinity Purified

Aufreinigung: Affinity Purified

Immunogen: Between AA 262 and 312

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise:

IHC: 1:500 - 1:2,000. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.

IP: 2 - 10 μg/mg lysate

WB: 1:2,000 - 1:10,000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Haltbarkeit: 12 months

Details zu AIMP1

Target: AIMP1 (Aminoacyl tRNA Synthetase Complex-Interacting Multifunctional Protein 1 (AIMP1))

Andere Bezeichnung: AIMP1/EMAPII/SCYE1

Hintergrund: Background: Aminoacyl tRNA synthase complex-interacting multifunctional protein 1 (AIMP1) is a cytokine that is specifically induced by apoptosis, and it is involved in the control of angiogenesis, inflammation, and wound healing. The release of this cytokine renders the tumor-associated vasculature sensitive to tumor necrosis factor. The precursor protein is identical to the p43 subunit, which is associated with the multi-tRNA synthetase complex, and it modulates aminoacylation activity of tRNA synthetase in normal cells. This protein is also involved in the stimulation of inflammatory responses after proteolytic cleavage in tumor cell [taken from NCBI Entrez Gene (Gene ID: 9255)].

Gen-ID: 9255

NCBI Accession: NP_004748

UniProt: Q12904