PHGDH Antikörper (AA 1-50)
Kurzübersicht für PHGDH Antikörper (AA 1-50) (ABIN7455052)
Target
Alle PHGDH Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
-
-
Bindungsspezifität
- AA 1-50
-
Verwendungszweck
- Rabbit anti-PHGDH Antibody, Affinity Purified
-
Homologie
- Bovine,Pig,Orangutan,Chimpanzee
-
Aufreinigung
- Affinity Purified
-
Immunogen
- Between AA 1 and 50
-
Isotyp
- IgG
-
-
-
-
Applikationshinweise
-
IHC: 1:500 to 1:2,000. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.
IP: 2 - 10 μg/mg lysate
WB: 1:2,000 - 1:10,000
-
Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
-
-
Konzentration
- 1000 μg/mL
-
Buffer
- Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide
-
Konservierungsmittel
- Sodium azide
-
Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Lagerung
- 4 °C
-
Haltbarkeit
- 12 months
-
-
- PHGDH (phosphoglycerate Dehydrogenase (PHGDH))
-
Andere Bezeichnung
- PHGDH
-
Hintergrund
- Background: D-3-phosphoglycerate dehydrogenase (PHGDH) is an enzyme involved in the early steps of L-serine synthesis in animal cells. L-serine is required for D-serine and other amino acid synthesis. The enzyme requires NAD/NADH as a cofactor and forms homotetramers for activity. Mutations in this gene have been found in a family with congenital microcephaly, psychomotor retardation and other symptom [taken from NCBI Entrez Gene (Gene ID: 26227)].
-
Gen-ID
- 26227
-
NCBI Accession
- NP_006614
-
UniProt
- O43175
-
Pathways
- Metabolism of Steroid Hormones and Vitamin D, Warburg Effekt
Target
-