LRPPRC Antikörper (AA 1344-1394)

Produktnummer ABIN7455051

Produktdetails anti-LRPPRC Antikörper

Target: LRPPRC (Leucine-Rich PPR-Motif Containing (LRPPRC))

Bindungsspezifität: AA 1344-1394

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser LRPPRC Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))

Verwendungszweck: Rabbit anti-LRPPRC Antibody, Affinity Purified

Aufreinigung: Affinity Purified

Immunogen: Between AA 1344 and 1394

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise:

IHC: 1:500 - 1:2,000. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.

IP: 2 - 10 μg/mg lysate

WB: 1:2,000 - 1:10,000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Haltbarkeit: 12 months

Details zu LRPPRC

Target: LRPPRC (Leucine-Rich PPR-Motif Containing (LRPPRC))

Andere Bezeichnung: LRPPRC (LRPPRC Produkte)

Hintergrund: Background: LRPPRC is a leucine-rich protein that has multiple pentatricopeptide repeats (PPR). The precise role of this protein is unknown but studies suggest it may play a role in cytoskeletal organization, vesicular transport, or in transcriptional regulation of both nuclear and mitochondrial genes. The protein localizes primarily to mitochondria and is predicted to have an N-terminal mitochondrial targeting sequence. Mutations in this gene are associated with the French-Canadian type of Leigh syndrome [taken from NCBI Entrez Gene (Gene ID: 10128)].

Gen-ID: 10128

NCBI Accession: NP_573566

UniProt: P42704