LRPPRC Antikörper (AA 847-876)

Produktnummer ABIN6243782

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch LRPPRC in WB. Es zeigt Reaktivität gegenüber Proben von Human und Maus.

Kurzübersicht für LRPPRC Antikörper (AA 847-876) (ABIN6243782)

Target: LRPPRC (Leucine-Rich PPR-Motif Containing (LRPPRC))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser LRPPRC Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Klon: RB53981

Produktdetails anti-LRPPRC Antikörper

Bindungsspezifität: AA 847-876

Homologie: Rat

Aufreinigung: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This LRPPRC antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 847-876 amino acids from the Central region of human LRPPRC.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: WB: 1:2000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Haltbarkeit: 6 months

Details zu LRPPRC

Target: LRPPRC (Leucine-Rich PPR-Motif Containing (LRPPRC))

Andere Bezeichnung: LRPPRC

Hintergrund: May play a role in RNA metabolism in both nuclei and mitochondria. In the nucleus binds to HNRPA1-associated poly(A) mRNAs and is part of nmRNP complexes at late stages of mRNA maturation which are possibly associated with nuclear mRNA export. May bind mature mRNA in the nucleus outer membrane. In mitochondria binds to poly(A) mRNA. Plays a role in translation or stability of mitochondrially encoded cytochrome c oxidase (COX) subunits. May be involved in transcription regulation. Cooperates with PPARGC1A to regulate certain mitochondrially encoded genes and gluconeogenic genes and may regulate docking of PPARGC1A to transcription factors. Seems to be involved in the transcription regulation of the multidrug-related genes MDR1 and MVP. Part of a nuclear factor that binds to the invMED1 element of MDR1 and MVP gene promoters. Binds single-stranded DNA (By similarity).

Molekulargewicht: 157905

UniProt: P42704