SMC1A Antikörper (AA 1183-1233)
Kurzübersicht für SMC1A Antikörper (AA 1183-1233) (ABIN7454968)
Target
Alle SMC1A Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 1183-1233
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Verwendungszweck
- Goat anti-SMC1 Antibody, Affinity Purified
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Homologie
- Rat,Bovine
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Aufreinigung
- Affinity Purified
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Immunogen
- Between AA 1183 and 1233
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Isotyp
- IgG
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Applikationshinweise
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IHC: 1:500 - 1:2,000. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.
IP: 2 - 10 μg/mg lysate
WB: 1:2,000 - 1:10,000
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Konzentration
- 1000 μg/mL
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Buffer
- Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- 4 °C
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Haltbarkeit
- 12 months
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- SMC1A (Structural Maintenance of Chromosomes 1A (SMC1A))
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Andere Bezeichnung
- SMC1
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Hintergrund
- Background: Structural maintenance of chromosomes (SMC) proteins are part of the cohesin and condensin multisubunit complexes that play a critical role in chromosome organization, segregation, gene regulation, and DNA repair. The core cohesin complex includes a heterodimer of SMC1 and SMC3 that functions by forming a ring-like structure that holds sister chromatids together. Cohesin is important to sister chromatid separation and segregation during mitosis and meiosis and also plays a role in double-strand break repair by homologous recombination.
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Gen-ID
- 8243
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NCBI Accession
- NP_006297
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UniProt
- Q14683
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Pathways
- Stem Cell Maintenance
Target
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