FNBP1L Antikörper (AA 450-500)
Kurzübersicht für FNBP1L Antikörper (AA 450-500) (ABIN7454919)
Target
Alle FNBP1L Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 450-500
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Verwendungszweck
- Rabbit anti-Toca-1 Antibody, Affinity Purified
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Aufreinigung
- Affinity Purified
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Immunogen
- between AA 450 and 500
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Isotyp
- IgG
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Applikationshinweise
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IHC: 1:500 - 1:2,000. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.
IP: 2 - 10 μg/mg lysate
WB: 1:2,000 - 1:10,000
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Konzentration
- 1000 μg/mL
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Buffer
- Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- 4 °C
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Haltbarkeit
- 12 months
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- FNBP1L (Formin Binding Protein 1-Like (FNBP1L))
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Andere Bezeichnung
- Toca-1
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Hintergrund
- Background: Toca-1 is required to coordinate membrane tubulation with reorganization of the actin cytoskeleton during endocytosis. Toca-1 may bind to lipids such as phosphatidylinositol 4,5-bisphosphate and phosphatidylserine and promote membrane invagination and the formation of tubules. Toca-1 also promotes CDC42-induced actin polymerization by activating the WASL/N-WASP-WASPIP/WIP complex, the predominant form of WASL/N-WASP in cells [taken from the Universal Protein Resource (UniProt) Q5T0N5].
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Gen-ID
- 54874
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NCBI Accession
- NP_001157945
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UniProt
- Q5T0N5
Target
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