HEXIM1 Antikörper (AA 175-225)
Kurzübersicht für HEXIM1 Antikörper (AA 175-225) (ABIN7454895)
Target
Alle HEXIM1 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 175-225
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Verwendungszweck
- Rabbit anti-HEXIM1 Antibody, Affinity Purified
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Homologie
- Rat,Bovine
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Aufreinigung
- Affinity Purified
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Immunogen
- between AA 175 and 225
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Isotyp
- IgG
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Applikationshinweise
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IHC: 1:200 - 1:1,000. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.
IP: 2 - 10 μg/mg lysate
WB: 1:2,000 - 1:10,000
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Konzentration
- 200 μg/mL
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Buffer
- Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- 4 °C
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Haltbarkeit
- 12 months
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- HEXIM1 (Hexamethylene Bis-Acetamide Inducible 1 (HEXIM1))
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Andere Bezeichnung
- HEXIM1
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Hintergrund
- Background: Hexamethylene bis-acetamide-inducible protein 1 (HEXIM1) is a transcriptional regulator which functions as a general RNA polymerase II transcription inhibitor. In cooperation with 7SK snRNA, HEXIM1sequesters P-TEFb in a large inactive 7SK snRNP complex preventing RNA polymerase II phosphorylation and subsequent transcriptional elongation. HEXIM1 may also regulate NF-kappa-B, ESR1, NR3C1 and CIITA-dependent transcriptional activity [taken from the Universal Protein Resource (UniProt) O94992].
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Gen-ID
- 10614
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NCBI Accession
- NP_006451
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UniProt
- O94992
Target
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