Vinculin Antikörper (AA 1016-1066)
Kurzübersicht für Vinculin Antikörper (AA 1016-1066) (ABIN7454836)
Target
Alle Vinculin (VCL) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 1016-1066
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Verwendungszweck
- Rabbit anti-Vinculin Antibody, Affinity Purified
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Homologie
- Rat,Chicken,Pig
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Aufreinigung
- Affinity Purified
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Immunogen
- between AA 1016 and 1066
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Isotyp
- IgG
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Applikationshinweise
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IHC: 1:500 - 1:2,000. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.
IP: 5 - 15 μg/mg lysate
WB: 1:2,000 - 1:10,000
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Konzentration
- 1000 μg/mL
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Buffer
- Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- 4 °C
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Haltbarkeit
- 12 months
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- Vinculin (VCL)
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Andere Bezeichnung
- Vinculin
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Hintergrund
- Background: Vinculin is a cytoskeletal protein associated with cell-cell and cell-matrix junctions, where it is thought to function as one of several interacting proteins involved in anchoring F-actin to the membrane. Defects in vinculin are the cause of cardiomyopathy dilated type 1W, a disorder characterized by ventricular dilation and impaired systolic function, resulting in congestive heart failure and arrhythmia [taken from NCBI Entrez Gene (GeneID: 7414)].
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Gen-ID
- 7414
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NCBI Accession
- NP_003364
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UniProt
- P18206
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Pathways
- Cell-Cell Junction Organization, Maintenance of Protein Location, Signaling Events mediated by VEGFR1 and VEGFR2
Target
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