Vinculin Antikörper (N-Term)

Produktnummer ABIN391625

Produktdetails anti-Vinculin Antikörper

Target: Vinculin (VCL)

Bindungsspezifität: AA 12-39, N-Term

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Vinculin Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Homologie: C, Pig

Aufreinigung: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Immunogen: This VINC antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 12-39 amino acids from the N-terminal region of human VINC.

Klon: RB15469

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: WB: 1:1000. WB: 1:1000. WB: 1:2000. IHC-P: 1:10~50

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Haltbarkeit: 6 months

Details zu Vinculin

Target: Vinculin (VCL)

Andere Bezeichnung: Vinculin (VCL Produkte)

Synonyme: CMD1W antikoerper, CMH15 antikoerper, MV antikoerper, MVCL antikoerper, VCL antikoerper, im:6902790 antikoerper, hm:zehn2160 antikoerper, DDBDRAFT_0186762 antikoerper, DDBDRAFT_0232320 antikoerper, DDB_0186762 antikoerper, DDB_0232320 antikoerper, 9430097D22 antikoerper, AA571387 antikoerper, AI462105 antikoerper, AW545629 antikoerper, CG3299 antikoerper, CT11081 antikoerper, Dmel\\CG3299 antikoerper, Dmvincp antikoerper, EG:103B4.1 antikoerper, Vin antikoerper, Vin2EF antikoerper, vinc antikoerper, LOC100228062 antikoerper, vcl-A antikoerper, vinculin antikoerper, vinculin a antikoerper, vinculin A antikoerper, Vinculin antikoerper, vinculin S homeolog antikoerper, VCL antikoerper, vcla antikoerper, vinA antikoerper, Vcl antikoerper, Vinc antikoerper, CpipJ_CPIJ013873 antikoerper, Bm1_37935 antikoerper, vcl antikoerper, vcl.S antikoerper

Hintergrund: VINC is a cytoskeletal protein associated with cell-cell and cell-matrix junctions, where it is thought to function as one of several interacting proteins involved in anchoring F-actin to the membrane. Defects in VCL are the cause of cardiomyopathy dilated type 1W. Dilated cardiomyopathy is a disorder characterized by ventricular dilation and impaired systolic function, resulting in congestive heart failure and arrhythmia.

Molekulargewicht: 123799

Gen-ID: 7414

NCBI Accession: NP_003364, NP_054706

UniProt: P18206

Pathways: Cell-Cell Junction Organization, Maintenance of Protein Location, Signaling Events mediated by VEGFR1 and VEGFR2