CENPF Antikörper (AA 2350-2400)
Kurzübersicht für CENPF Antikörper (AA 2350-2400) (ABIN7454765)
Target
Alle CENPF Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 2350-2400
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Verwendungszweck
- Rabbit anti-CENP-F/Mitosin Antibody, Affinity Purified
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Aufreinigung
- Affinity Purified
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Immunogen
- between AA 2350 and 2400
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Isotyp
- IgG
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Applikationshinweise
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IHC: 1:200 - 1:1,000. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.
IP: 2 - 5 μg/mg lysate
WB: 1:2,000 - 1:10,000
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Konzentration
- 200 μg/mL
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Buffer
- Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- 4 °C
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Haltbarkeit
- 12 months
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- CENPF (Centromere Protein F (CENPF))
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Andere Bezeichnung
- CENP-F/Mitosin
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Hintergrund
- Background: Centromere protein F (CENP-F) is a microtubule binding protein and component of the kinetochore. It is essential for kinetochore attachment, chromosome alignment, and the spindle checkpoint. CENP-F appears to be important to the association of the NudE-related proteins Ndel1 and Nde1 to the Lis1/dynein motor complex and their role in kinetochore function. CENP-F is a farnesylated protein and the farnesylation of CENP-F appears to be central to its role in mediating kinetochore-microtubule interactions as well as its degradation after mitosis. Recently, CENP-F expression has been correlated with markers of poor outcome in breast cancer.
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Gen-ID
- 1063
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UniProt
- P49454
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Pathways
- Chromatin Binding, M Phase, SARS-CoV-2 Protein Interaktom, Phosphorylierungen bei SARS-CoV-2 Infektion
Target
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